Bioorganic Chemistry and Bio-Crystallography laboratory (B₂Cl)

Possible thesis projects include the study of pathogenicity factors from Erwinia amylovora the bacterium responsible for fire blight of apple and pear trees .

Supervisor	Topics	Title	Techniques involved
Benini Stefano	Protein science, Structural biology	Molecular characterization of the bio synthetic pathway of amylovoran, a pathogenicity factor in Erwinia amylovora	- Molecular biology, protein purification and crystallisation, X-ray data analysis
Benini Stefano	Protein science, Structural biology	Biomolecular study of iron uptake by desferrioxamine in the plant pathogen Erwinia amylovora	- Molecular biology, protein purification and crystallisation, X-ray data analysis
Benini Stefano	Protein science, Structural biology	Secreted proteins of Erwinia amylovora	- Molecular biology, protein purification and crystallisation, X-ray data analysis

The techniques used during your work will span over a wide range of laboratory molecular biology techniques: bacterial growth, gene cloning and protein overexpression in Escherichia coli, protein purification and crystallisation. The work will be carried out in the laboratory of bioorganic chemistry and bio-crystallography of the Faculty of Science and Technology.