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Bioorganic Chemistry and Bio-Crystallography laboratory (B2Cl)
The
laboratory of Bioorganic chemistry and
Bio-Crystallography (B2Cl) is devoted to the study of organic
molecules involved in biological processes such as proteins, enzymes,
carbohydrates and DNA. Form March 2009 the laboratory has
been created to mainly develop structural biology in the region and to
study organisms with a link to the local economy. In this framework
the study of the phytopathogenic bacterium Erwinia amylovora
has played a pivotal role. E. amylovora is the causative
agent of Fireblight in Rosaceae
as apple, pear, raspberry and several ornamentals.
We
are mostly specialized on structural biology by X-ray crystallography, the most
powerful tool to investigate biomolecules at the atomic level. We have
collaboration with prestigious scientific institutions such as the European Molecular Biology Laboratory
(EMBL-Hamburg), DIAMOND synchrotron (UK),
the Department of
Biological Chemistry at the John Innes Centre (JIC) UK, the Department of Crop science at the University of
Illinois and the Department of
Pharmacy and Biotechnology, University of Bologna.